What should be the treatment for a 50-year-old woman experiencing a rash and itching after starting penicillin?

In the case of a 50-year-old woman experiencing a rash and itching after starting penicillin, the most appropriate treatment is to provide transport only with close monitoring. This approach is suitable for managing mild allergic reactions, such as localized rashes or itching, which do not involve more severe symptoms like difficulty breathing, swelling of the face or throat, or severe hypotension.

Close monitoring during transport is critical; it allows for observation of the patient's symptoms, ensuring that if they worsen, additional interventions can be taken. Anaphylaxis or severe allergic reactions would warrant more urgent treatments, such as epinephrine and rapid transport, but these would only be indicated if systemic symptoms were present.

Warm compresses could offer some relief for itching but do not address the underlying issue of the allergic reaction or the need for medical evaluation. Thus, while they may help with comfort, they do not provide a comprehensive approach to the situation.