Which clinical sign would NOT be expected in a patient who overdosed on methamphetamine?

In the context of a methamphetamine overdose, bradycardia, which refers to an abnormally slow heart rate, would not be expected. Methamphetamine is a powerful central nervous system stimulant that typically causes an increase in overall sympathetic nervous system activity. This stimulation leads to an array of physiological responses, including an increased heart rate (tachycardia), elevated blood pressure (hypertension), heightened levels of agitation, and dilation of the pupils (mydriasis).

In patients who have overdosed on methamphetamine, one would observe agitation due to increased energy and restlessness, along with other signs such as hypertension as a result of the stimulant effects on the cardiovascular system. Similarly, dilated pupils are a common response to sympathomimetic drug use, which includes substances like methamphetamine. Therefore, the presence of these signs aligns with what is typically seen in such cases, while bradycardia runs counter to the expected physiological response to an overdose of this stimulant.