Which drug can cause or worsen excited delirium?

Cocaine is known to stimulate the central nervous system, leading to increased levels of neurotransmitters like dopamine and norepinephrine. This heightened stimulation can induce symptoms of excited delirium, which is characterized by severe agitation, confusion, and aggressive behavior. The use of cocaine can lead to extreme paranoia, hallucinations, and unpredictable behavior, all of which contribute to the risk of developing excited delirium.

In contrast, other substances included in the options, such as heroin, generally lead to sedation and respiratory depression rather than excitatory symptoms. Ketamine, while it can cause dissociation and delirium, does not typically induce the same level of agitation commonly associated with excited delirium. Marijuana might lead to altered mental states but is less directly linked to the severe excitation and agitation seen in excited delirium compared to cocaine.